Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp211 | Muscle, physical activity and bone | ECTS2014

The peroxisome proliferator-activated receptor α agonist fenofibrate improves the effect of high-impact exercise on bone and muscle mass in ovariectomized rats

Mosti Mats Peder , Ericsson Madelene , Syversen Unni , Stunes Astrid Kamilla

Estrogen deficiency promotes bone loss and skeletal muscle dysfunction. Peroxisome proliferator-activated receptor (PPAR) agonists and high-impact exercise both affect musculoskeletal properties. Whereas PPARδ agonists ameliorate training response in muscle, PPARα agonists exert beneficial effects in bone and muscle. In the present study we investigated the effects of the PPARα agonist fenofibrate and high-impact jumping exercise alone and combined in ovariectom...